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The human leukocyte antigen (HLA) region of chromosome 6 contains genes associated with an elevated risk of MS, including HLA-DR2 + , HLA-DQ6, DQA 0102, DQB1 0602, HLA-DRB1, DR15, DRB1*1501, and DRB1*1503

[PubMed: 12479844] 60

Suggested cutoffs and the interpretation of values of the combined 4cB12 indicator for use by researchers and clinicians and for epidemiologic purposes are shown in Table 22b.10

DOI: 10.1111/cen.13268 27

Bacteriostatic water degradation signals include visible cloudiness or particulate matter, a faint sweet or chemical odour indicating benzyl alcohol breakdown, pH drift below 4.5 or above 7.0 (testable with indicator strips), storage beyond 28 days post-puncture, or any temperature excursion above 25C for more than 6 hours